When Propofol is Problematic

نویسنده

  • Phil G. Morgan
چکیده

Figure 1. Representation of the electron transport chain showing the relationship of complexes I-V. Note that I and II both feed into III via the intermediate ubiquinone. Cytochrome c then receives electrons from III and passes them to complex IV. Electron flow is linked to protons pumped out of the matrix (dotted arrows). Proton gradient drives ATP formation by F0F1 ATPase (complex V). Propofol inhibits mitochondrial function at multiple sites.

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تاریخ انتشار 2007